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osteomalacia

osteomalacia is a topic covered in the Taber's Medical Dictionary.

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(os″tē-ō-mă-lā′sh(ē-)ă )

[osteo- + -malacia]
An abnormality of new bone formation (osteoid) causing bones to become increasingly soft, flexible, brittle, and deformed. An adult form of rickets, osteomalacia can also be traced to liver disease, cancer, or other ailments that inhibit the normal metabolism of vitamin D.
SEE: rickets
osteomalacic (os″tē-ō-mă-lā′sik ), adj.

CAUSES
The disease is often caused by any of the many vitamin D-deficiency disorders or diseases in which there is resistance to the effect of vitamin D on the skeleton, or by deranged phosphorus metabolism, chronic kidney disease, or renal tubular acidosis (among other more rare illnesses).

SYMPTOMS AND SIGNS
Clinical findings include bone and joint pains, e.g., in the limbs, lumbar spine, thorax, and pelvis; fractures; anemia; impaired gait, and progressive weakness.

DIAGNOSIS
Affected bones have a classical appearance on radiological imaging.

TREATMENT
Ergocalciferol and calcium are given as nutritional supplements to patients with vitamin D-deficient diets.

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Citation

Venes, Donald, editor. "Osteomalacia." Taber's Medical Dictionary, 23rd ed., F.A. Davis Company, 2017. Taber's Online, www.tabers.com/tabersonline/view/Tabers-Dictionary/770141/all/osteomalacia.
Osteomalacia. In: Venes D, ed. Taber's Medical Dictionary. 23rd ed. F.A. Davis Company; 2017. https://www.tabers.com/tabersonline/view/Tabers-Dictionary/770141/all/osteomalacia. Accessed August 20, 2019.
Osteomalacia. (2017). In Venes, D. (Ed.), Taber's Medical Dictionary. Available from https://www.tabers.com/tabersonline/view/Tabers-Dictionary/770141/all/osteomalacia
Osteomalacia [Internet]. In: Venes D, editors. Taber's Medical Dictionary. F.A. Davis Company; 2017. [cited 2019 August 20]. Available from: https://www.tabers.com/tabersonline/view/Tabers-Dictionary/770141/all/osteomalacia.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC T1 - osteomalacia ID - 770141 ED - Venes,Donald, BT - Taber's Medical Dictionary UR - https://www.tabers.com/tabersonline/view/Tabers-Dictionary/770141/all/osteomalacia PB - F.A. Davis Company ET - 23 DB - Taber's Online DP - Unbound Medicine ER -