rejection

rejection is a topic covered in the Taber's Medical Dictionary.

To view the entire topic, please or .

Taber’s Cyclopedic Medical Dictionary 24th Edition Online + App from F.A. Davis and Unbound Medicine. Find 75,000 medical and nursing definitions. Download to iPhone, iPad, and Android. Explore these free sample topics:

-- The first section of this topic is shown below --

(rĕ-jek′shŏn)

To hear audio pronunciation of this topic, purchase a subscription or log in.

[L. rejectio, a throwing back]

1. Refusal to accept or to show affection. In animals, for example, the young may be ignored or driven away by their mother.
2. In tissue and organ transplantation, destruction of transplanted material at the cellular level by the host's immune mechanism. Transplant rejection is controlled primarily by T cells, but macrophages and B lymphocytes are also involved. Maintenance immunosuppressive therapy with cyclosporine, mycophenolate, and tacrolimus, which inhibit or block T-cell activity, lowers the risk of transplant organ rejection. Monoclonal and polyclonal antibody therapies are saved for acute rejection.

-- To view the remaining sections of this topic, please or --

(rĕ-jek′shŏn)

To hear audio pronunciation of this topic, purchase a subscription or log in.

[L. rejectio, a throwing back]

1. Refusal to accept or to show affection. In animals, for example, the young may be ignored or driven away by their mother.
2. In tissue and organ transplantation, destruction of transplanted material at the cellular level by the host's immune mechanism. Transplant rejection is controlled primarily by T cells, but macrophages and B lymphocytes are also involved. Maintenance immunosuppressive therapy with cyclosporine, mycophenolate, and tacrolimus, which inhibit or block T-cell activity, lowers the risk of transplant organ rejection. Monoclonal and polyclonal antibody therapies are saved for acute rejection.

There's more to see -- the rest of this entry is available only to subscribers.