[L. nodulus, little knot]
1. A small node.
2. A small cluster of cells.
A group of unencapsulated lymph nodules, such as Peyer patches of the small intestine.
SEE: Albini nodules
apple jelly nodule
The jelly-like lesion of lupus vulgaris.
SEE: Aschoff nodules
Lymph nodules located in the cortex of a lymph node.
SEE: Singer's node.
A mass of compact, densely staining lymphocytes forming the structural unit of lymphatic tissue. These nodules may occur singly, in groups (as in Peyer patches), or in encapsulated organs such as lymph nodes. Each contains a lighter-staining germinal center where new lymphocytes are formed.
SYN: SEE: lymphoid nodule
SEE: Lymph nodule
A small round density, 1 to 5 mm in diameter, as seen on the chest radiograph, e.g., in disseminated tuberculosis.
A painless smooth or warty lesion due to a poxvirus that is transmitted from the udders of infected cows to the hands of milkers.
A subcutaneous node of fibrous tissue that may be present in patients with rheumatic fever.
SEE: subcutaneous nodule for illus.
SEE: Schmorl node.
nodule of the semilunar valve
An Arantius body.
SEE: Arantius, Julius Caesar
A small brown nodule seen in the spleen and other organs and consisting of necrotic tissue encrusted by iron salts.
An isolated nodule of lymphatic tissue such as occurs in mucous membranes.
solitary pulmonary nodule
Any isolated mass lesion found in the lung, usually during an x-ray study performed for another reason. Most small masses that are identified in this way are benign, although smokers, patients already known to have cancer in another organ system, and older patients have an increased risk that a solitary nodule will be a new malignancy or a metastasis from another source.
The first step in evaluating a solitary lung nodule is to search for prior chest x-ray films. If the nodule can be found on films done many months or years earlier and has not changed in size, shape, or calcification, it is likely to be benign and can be followed conservatively. Newly identified lesions within the lung that were not previously present usually are evaluated with further studies, such as computed tomography of the lungs, sputum studies, or biopsies.
A small, nontender swelling resembling Aschoff bodies and found over bony prominences in persons with rheumatic fever or rheumatoid arthritis (in rheumatoid arthritis, it is called a rheumatoid nodule).
Nodular swelling and possible bone changes of the area of the lower leg and foot exposed to pressure and trauma while on a surfboard. The nodules may be painful.
SYN: SEE: surfer's knots
A visible or palpable mass in the thyroid gland, benign about 90% to 95% of the time. A history of radiation to the head or neck increases the likelihood that the lesion will be malignant, as does the appearance of the nodule in the first decades of life. Fine-needle aspiration biopsy is the first and often the definitive diagnostic test.
Patients can be reassured that more than 99% of benign thyroid nodules remain benign after 5 years of follow-up.
A nodule characteristic of typhoid fever and found in the liver.
A small nodule of the skin seen in typhus. They are composed of mononuclear cell infiltration around vessels.