Taber's Cyclopedic Medical Dictionary, 21st Edition

Naphthalene

Naphthalene

Substance
Naphthalene

Pathology
Metabolism to numerous by-products including alpha-napthol, a potent hemolytic agent.

Symptoms
Fever, nausea, vomiting, abdominal pain, diarrhea, lethargy, seizures, hemolysis, pallor, jaundice, cyanosis.

Emergency Measures
Activated charcoal; IV hydration and urinary alkalinization; transfusions for hemolysis.

Comments
Hemolysis is acute and severe in patients with glucose-6-phosphate dehydrogenase deficiency. Naphthalene is used in mothballs and toilet bowl cleaners, but less toxic agents are available.

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