Substance
Chlorinated hydrocarbon pesticides

[Other Names]
Aldrin
Chlordane
DDT (chlorophenothane)
Dieldrin
Heptachlor
Lindane
Thiodan
Toxaphene

Pathology
Direct toxicity to neuronal axons, interfering with transmission; affects myocardium stability resulting in arrhythmias.

Symptoms
Vomiting, headache, fatigue, tremors, ataxia, weakness, confusion, seizures, respiratory depression, arrhythmias, coma. In agents other than DDT, seizure may be first sign of toxicity.

Emergency Measures
Maintenance of airway, breathing, circulation; activated charcoal and cathartic; lavage for large ingestions; multiple-dose activated charcoal and cholestyramine to enhance removal; appropriate therapy for seizures and arrhythmias.

Comments
These agents can be absorbed transdermally and by inhalation. Toxicity and outcomes vary.