Taber's Cyclopedic Medical Dictionary, 21st Edition

Carbon tetrachloride

Carbon tetrachloride

Substance
Carbon tetrachloride

Pathology
Metabolites cause renal and hepatic toxicity; potent CNS depressant effects.

Symptoms
Nausea, vomiting, abdominal pain, headache, confusion, drowsiness, coma, renal and hepatic failure. Death is caused by respiratory arrest, circulatory collapse, or ventricular fibrillation.

Emergency Measures
Airway maintenance and ventilation assistance, gastric lavage, activated charcoal and cathartic, acetylcysteine to decrease effects of intermediate metabolite.

Comments
Toxicity from inhalation can be severe; small ingestions (<10 ml) can be fatal.

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