Taber's Cyclopedic Medical Dictionary, 21st Edition

antigen-presenting cell

Abbreviation: APC.
A cell that breaks down antigens and displays their fragments on surface receptors next to major histocompatibility complex molecules. This presentation is necessary for some T lymphocytes that are unable to recognize soluble antigens. Macrophages are the primary antigen-presenting cells, but B cells and dendritic cells also can act as APCs.

See: T cell; macrophage processing

Main entry:
cell



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